The course provides comprehensive multidisciplinary training in genome sequencing, advancing computing, programming, data reproducibility, open science, and specialized bioinformatics.
The course will be in French, but the slides and other course material will be in English.
| Module | Description | Hours | Instructors |
|---|---|---|---|
| Course review | General biology, Genomics basis, Genome Structure and Dynamics / Evolution, Sequencing technologies and Applications | 36h | |
| Sequencing: from library preparation to sequencing | Overview of Sequencing Technologies, RNA/DNA Extraction, Library Preparation for Illumina and ONT, Sequencing and Quality Control | 30h | Martine Bangratz, Pakyendou Estel NAME, Dr. Cyrielle NDOUGONNA |
| Biological database | Sequence Databases (e.g., NCBI/SWISS-Prot), Blast Alignment, Primer design | 12h | Dr. Ezechiel TIBIRI, Dr. Christine TRANCHANT |
| Introduction to Algorithmics | Introduction to algorithms, data and control structures, with simplified exercises to acquire the basics, reused later in R and Python. | 8h | Dr. Ezechiel TIBIRI, Dr. Christine TRANCHANT, Dr. Koissi SAVI, Dr. Cyrielle NDOUGONNA |
| Linux | Basic Linux Commands, Bioinformatics Tools (e.g., BLAST), Advanced Linux (e.g., sed, awk), VCF, GFF Manipulation, slurm, Containers (Singularity, Conda) | 16h | Dr. Ezechiel TIBIRI, Dr. Christine TRANCHANT, Pakyendou Estel NAME |
| OMICs data analysis | Diversity analysis / metagenomic analysis (ONT and illumina sequencing, Sequence Quality, Mapping, Structural Variant detection, SNP Annotation) | 40h | Alexis DEREEPER, Dr Christine TRANCHANT, Dr. Ezechiel TIBIRI, Dr. Palwendé Romuald BOUA, Pakyendou Estel NAME |
| Data analysis and visualization in R | Read Tabular File into DataFrame, DataFrame Manipulation, Data Visualization (Plotting), R Markdown | 20h | Dr. Koissi SAVI, Dr. Richard DAMIEN, Dr. Palwendé Romuald BOUA |
| Python programming | Variables, Display, Lists, Loops and Comparisons, Tests, Files, Modules, Functions, Containers, Dictionaries, Tuples, and Sets | 20h | Julie ORJUELA, Dr. Ezechiel TIBIRI, Dr. Christine TRANCHANT, Pakyendou Estel NAME |
| Science reproductibility | Best Practices (Data Management, Code, Licensing), Containers (Docker, Singularity), Conda, Git, Snakemake | 10h | Julie ORJUELA, Dr. Ezechiel TIBIRI, Dr. Christine TRANCHANT, Pakyendou Estel NAME, Dr. Koissi SAVI, Ndomassi TANDO |